Albendazol

Albendazol

Albendazol CAS:54965-21-8

Albendazol Chemical Properties

MF: C12H15N3O2S

MW: 265,33

EINECS: 259-414-7

Ponto de fusão: 208-210 ° c

Densidade: 1,2561 (estimativa aproximada)

Índice de refração: 1,6740 (estimativa)

Solubilidade praticamente insolúvel em água, muito solúvel em ácido fórmico anidro, muito pouco solúvel em cloreto de metileno, praticamente insolúvel em etanol (96 por cento).

Pka: 10,72 ± 0,10 (previsto)

Solubilidade em água: 0,75mg / L (209ºC)

Albendazol CAS:54965-21-8 Especificação:

Albendazol CAS:54965-21-8 Introduction:

1. Albendazol is a kind of broad spectrum thiabendazole class anthelmintics which can be applied by both human and animal.

2. Albendazol can inhibit the parasite growth and reproduction by inhibiting the intestinal and absorbing the intracellular protein, resulting in the failure of parasite in sugar uptake which is indispensable for their survival, thus causing the endogenous glycogen depletion of insects and further inhibiting fumarate reductase system, preventing the generation of adenosine triphosphate, causing that the parasites are not be able to further survive and reproduce, and ultimately die due to energy depletion.

Albendazol CAS:54965-21-8 Functions

Albendazol is an anthelmintic or anti- worm medication. It prevents newly hatched insect larvae (worms) from growing or multiplying in your body.  

Albendazol is used to treat certain infections caused by worms such as pork tapeworm and dog tapeworm.

1. Albendazol is highly effective broad spectrum anthelmintic drugs, is benzimidazole deworming drugs in the broader spectrum.

2. Albendazol is highly active against nematodes, schistosomes, tapeworms, but also significantly inhibited the development of eggs.

3. Albendazol on parasitic nematodes in a variety of animals, schistosomes, tapeworms and cysticerci also has a significant role in repelling.

4. Albendazol is applied to get rid of roundworm, pinworm, hookworm, whipworm, can also be used for deworming livestock.

Albendazol CAS:54965-21-8 Application:

1. Antiparasitário de amplo espectro; Usado para expelir nematóides, tênias, vermes trematódeos e ectoparasitas na pecuária.

2. Albendazol has a broad spectrum of insect repellents, and has a strong effect on nematode, tapeworm and trematode; Its mechanism of action is to bind to microtubulin in the worm and prevent it polymerize withα-tubulin to form microtubules, thus affecting cell reproduction processes such as mitosis, protein assembly and energy metabolism.

3. A ivermectina tem um bom efeito sobre os parasitas internos e externos, especialmente insetos artrópodes e vermes nematóides internos; É usado principalmente para expulsar a nematodíase gastrointestinal, vermes pulmonares e ectoparasitas; O mecanismo de desparasitação é promover a liberação de GABA pelos neurônios pré-sinápticos, abrindo assim os canais de íon cloreto mediados pelo GABA; O fluxo de íons de cloro pode reduzir a resistência da membrana celular, causar a ligeira despolarização do potencial estático da membrana pós-sináptica, interferir na transmissão do sinal entre os músculos nervosos e também fazer com que o corpo do inseto relaxe e paralise, resultando na morte ou expulsão de o corpo do inseto.