Fenacetina

Fenacetina

Fenacetina CAS:62-44-2

Fenacetina Chemical Properties

MF: C10H13NO2

MW: 179,22

Ponto de fusão: 133-136 ° C (lit.)

Ponto de ebulição: 132 ° C / 4 mmHg

Densidade: 1,1248 (estimativa aproximada)

Fenacetina Specification:

Ensaio% ¥ 99,0

cloreto orgânico% <0,02

p-Fenetidinaâ ‰ ¤light redã € 4 #

Composto de carbono fácilâ € ¤4 # ã € 6 #

Perda na secagem% ¤ 0,5

Ponto de fusão: 134-137oC

Resíduo de ignição% ¤ 0,1

Fenacetina Introduction:

Fenacetina is a non-opioid analgesic without anti-inflammatory properties, inhibits COX-3 activity.Target: COXFenacetina is a pain-relieving and fever-reducing drug,

 Fenacetina was withdrawn from the Canadian market in June 1973 due to concerns regarding nephropathy. the clinical and laboratory data were compatible with“phenacetin nephritis”as described in Europe and Australia and recently in the United States and Canada.

This report evaluates the findings in the 23 cases and cautions against the use of phenacetin, particularly in patients with impaired renal function [1]. Fenacetina has been linked to renal papillary necrosis in human beings [2, 3].

Fenacetina Application:

Analgésico antipirético, usado para o tratamento de febre, dor de cabeça, neuralgia, etc.